|
|||||
 |
|
|
|
|
|
|
|
Modeling of
breast cancer through evolutionary game theory
Ke’Yona Barton, Corbin Smith, Jan Rychtář and Tsvetanka Sendova
Vol. 11 (2018), No. 4, 541–548
|
Abstract |
|
We present a simple mathematical model of the development and progression of breast cancer based on evolutionary game theory. Four types of cellular populations are considered: stromal (native) cells, macrophages, benign tumor cells, and motile (malignant) tumor cells. Despite the relative simplicity of the model, it provides a way to explore the interactions between the various cell types and suggests potential approaches to managing and treating cancer. |
Keywords
evolutionary game theory, mathematical modeling, breast
cancer
|
Mathematical Subject Classification 2010
Primary: 91A22
Secondary: 91A40
|
Milestones
Received: 13 January 2015
Revised: 8 July 2017
Accepted: 20 July 2017
Published: 15 January 2018
Communicated by Kenneth S. Berenhaut
|
Authors |
| Ke’Yona Barton | |
| Bennett College Greensboro, NC % 27401 United States |
|
| Corbin Smith | |
| Bennett College Greensboro, NC % 27401 United States |
|
| Jan Rychtář | |
| Department of Mathematics and
Statistics The University of North Carolina at Greensboro Greensboro, NC % 27412 United States |
|
| Tsvetanka Sendova | |
| Department of Mathematics Michigan State University East Lansing, MI % 48823 United States |
|
