We solve in the affirmative a
problem raised by B. S. Mityagin in 1961, namely, we prove that if (xn,fn) is a
biorthogonal system for a Banach space E with (fn) total over E, such that the set
of multipliers M(E,(xn,fn)) contains all sequences (𝜖i) with 𝜖i= ±1 for each i, then
(xn) is an unconditional basis for E.