Abstract

Theramechanics integrates mechanical principles and biological processes to offer innovative solutions for bone remodeling and the treatment of musculoskeletal diseases. This interdisciplinary approach builds upon continuum mechanics, thermodynamics, and mechanobiology, focusing on how mechanical stimuli drive cellular responses and influence biochemical interactions. By employing patient-specific computational models, theramechanics may enable the prediction of bone density evolution, the optimization of treatment protocols, and the improvement of fracture healing outcomes. The framework also provides a robust foundation for studying complex bone pathologies, such as osteoporosis and osteoarthritis, and supports the design of bioresorbable scaffolds for bone reconstruction. This paper explores the principles of theramechanics, highlights its applications in modeling and treatment, and discusses its potential to revolutionize personalized medicine for bone health.

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